No Template 1362-4962 x Poor metabolic health is a major issue for increased COVID­19 mortality in BAME groups 1 Malhotra Kamepalli Bamrah Journal Article Abstract Type 2 diabetes mellitus and hypertension are the most common comorbidities in patients with coronavirus infections. Emerging evidence demonstrates an important direct metabolic and endocrine mechanistic link to the viral disease process. Metabolic syndrome (METS) is a common denominator to these comorbidities and includes insulin resistance, dyslipidaemia, central obesity and hypertension, which are risk factors for the development of type 2 diabetes and cardiovascular diseases. In 2017, it was estimated that METS affected 20% of North American population, 25% of European population and approximately 15% of Chinese population. In this scenario, the relationship between METS and its comorbidities that aggravate the COVID-19 prognosis cannot be ignored. 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