Abstract
Endocarditis of a prosthetic valve is a known but rare occurrence. Fungal endocarditis is extremely rare. However, in the COVID-19 pandemic, there has been increasing recognition of fungal or yeast-related infections, often due to the combination of immune paresis, concurrent use of corticosteroids or underlying chronic conditions such as diabetes or neoplasms.
We present a patient with fulminating, invasive aspergillosis of a prosthetic aortic valve who presented with catastrophic cardiovascular failure needing intensive care management. Early recognition and prompt therapy is the cornerstone of success in such presentations with high mortality.
References
Najafi N, Moslemi A, Ghafari R, et al. Post-COVID-19 fatal Aspergillus endocarditis: A case report. Journal of Clinical Laboratory Analysis 2023;37:e24816. doi:10.1002/jcla.24816
Jalalian R, Shokohi T, Mirzakhani R, et al. Fatal Prosthetic Valve Endocarditis Due to Aspergillus flavus in a Diabetic Patient. IDR 2020;Volume 13:2245–50. doi:10.2147/IDR.S258637
Born T, Aruanno M, Kampouri E, et al. Aspergillus tubingensis Endocarditis: A Case Report and Review of the Literature. Mycopathologia 2022;187:249–58. doi:10.1007/s11046-022-00621-0
Meshaal MS, Labib D, Said K, et al. Aspergillus endocarditis: Diagnostic criteria and predictors of outcome, A retrospective cohort study. PLoS One 2018;13:e0201459. doi:10.1371/journal.pone.0201459
Zhang H, Zhang Y, Wu J, et al. Risks and features of secondary infections in severe and critical ill COVID-19 patients. Emerg Microbes Infect 2020;9:1958–64. doi:10.1080/22221751.2020.1812437
Musuuza JS, Watson L, Parmasad V, et al. Prevalence and outcomes of co-infection and superinfection with SARS-CoV-2 and other pathogens: A systematic review and meta-analysis. PLoS One 2021;16:e0251170. doi:10.1371/journal.pone.0251170
Kundu R, Singla N. COVID-19 and Plethora of Fungal Infections. Curr Fungal Infect Rep 2022;16:47–54. doi:10.1007/s12281-022-00432-2
Kalokhe AS, Rouphael N, El Chami MF, et al. Aspergillus endocarditis: a review of the literature. International Journal of Infectious Diseases 2010;14:e1040–7. doi:10.1016/j.ijid.2010.08.005
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Copyright (c) 2023 Array