Following the first few reports of a novel coronavirus affecting a large number of Chinese residents in the city of Wuhan, it was rapidly clear that the disease did not affect everyone to the same degree. Often this is based on socio-political factors, leadership and resilience of the public health infrastructure. The predicted surge in infections due to high viral transmission rates threatened to overwhelm every healthcare system in the world. However, it has become clear that the experience of different population groups or subsets with variable characteristics was not the same. This review assesses pre-existing conditions that were identified as pathophysiological or sociodemographic risk factors of COVID-19. This will allow policymakers to decide what mitigation is needed to reduce those risks and protect the public from infections.
Chen T, Wu D, Chen H, et al. Clinical characteristics of 113 deceased patients with coronavirus disease 2019: retrospective study. BMJ. 2020;368:m1091.
Wang B, Li R, Lu Z, Huang Y. Does comorbidity increase the risk of patients with COVID-19: evidence from meta-analysis. Aging (Albany NY). 2020;12(7):6049-6057.
Yang J, Zheng Y, Gou X, et al. Prevalence of comorbidities and its effects in patients infected with SARS-CoV-2: a systematic review and meta-analysis. Int J Infect Dis. 2020;94:91-95.
Wu Z, McGoogan JM. Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72 314 Cases From the Chinese Center for Disease Control and Prevention. JAMA. 2020.
Vardavas CI, Nikitara K. COVID-19 and smoking: A systematic review of the evidence. Tob Induc Dis. 2020;18:20.
Cai Q, Chen F, Wang T, et al. Obesity and COVID-19 Severity in a Designated Hospital in Shenzhen, China. Diabetes Care. 2020.
Lu X, Zhang L, Du H, et al. SARS-CoV-2 Infection in Children. N Engl J Med. 2020;382(17):1663-1665.
Wang J, Zhou M, Liu F. Reasons for healthcare workers becoming infected with novel coronavirus disease 2019 (COVID-19) in China. J Hosp Infect. 2020;105(1):100-101.
Li W, Zhang J, Xiao S, Sun L. Characteristics of deaths amongst health workers in China during the outbreak of COVID-19 infection. J Infect. 2020.
Docherty AH, EM. Green, CA. Hardwick, H. Nguyen-Van-Tam, JS. Dunning, J. Openshaw, PJM. Baillie, J. Semple, MG. Features of 16,749 hospitalised UK patients with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol; 2020.
Centre ICNAaR. ICNARC Report May 2020.
Williamson E, Walker A, Bhaskaran K, et al. OpenSAFELY: factors associated with COVID-19-related hospital death in the linked
electronic health records of 17 million adult NHS patients. ; 2020.
Stafford K, Hoyer M, Morrison A. Racial toll of virus grows even starker as more data emerges. Associated Press; 2020.
Lucyk K, McLaren L. Taking stock of the social determinants of health: A scoping review. PLoS One. 2017;12(5):e0177306.
Cook T, Kurusumovic E, Lennan S. Exclusive: deaths of NHS staff from covid-19 analysed. Health Services Journal; 2020.
Ferioli M, Cisternino C, Leo V, Pisani L, Palange P, Nava S. Protecting healthcare workers from SARS-CoV-2 infection: practical indications. Eur Respir Rev. 2020;29(155).
Dargaville T, Spann K, Celina M. Opinion to address a potential personal protective equipment shortage in the global community during the COVID-19 outbreak. Polym Degrad Stab. 2020:109162.
England PH. COVID-19 Personal Protective Equipment (PPE). In: Health Do ed; 2020.
Campbel D. NHS looks to taking BME staff off frontline for their safety. Guardian; 2020.
Jankowski JD, A.English, P.Friedman, E.McKeown, H.Rao, M. Sethi, S. Strain D. Risk Stratification for Healthcare workers during the CoViD-19 Pandemic; using demographics, co-morbid disease and clinical domain in order to assign clinical duties. MedRxiv; 2020.
Brody GH, Yu T, Miller GE, Chen E. Discrimination, racial identity, and cytokine levels among African-American adolescents. J Adolesc Health. 2015;56(5):496-501.
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