This article rationalises the culmination of the design, testing, regulatory approval and delivery of the SARS-CoV-2 vaccine in the UK, USA and across the world. The author champions the worldwide collaboration of scientists, industry, governments, regulatory agencies and several thousands of people who have courageously put themselves forward to make this immense feat possible. So that we, the rest of the people may reap the survival benefits. The author presents a balanced view and acknowledges the uncompromising science that has fuelled this marvel- encouraging people who fear the unknown and vaccine sceptics to come forward.
Fan, Y., et al., Bat Coronaviruses in China. Viruses, 2019. 11(3).
Marston, H.D., C.I. Paules, and A.S. Fauci, The Critical Role of Biomedical Research in Pandemic Preparedness. JAMA, 2017. 318(18): p. 1757-1758.
Lu, R., et al., Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding. Lancet, 2020. 395(10224): p. 565-574.
Krammer, F., SARS-CoV-2 vaccines in development. Nature, 2020. 586(7830): p. 516-527.
World Health Organisation, Novel Coronavirus Landscape 2019. 2020.
Polack, F.P., et al., Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine. N Engl J Med, 2020.
Pardi, N., et al., mRNA vaccines - a new era in vaccinology. Nat Rev Drug Discov, 2018. 17(4): p. 261-279.
Voysey, M., et al., Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK. Lancet, 2020.
COVID19 Genomics UK Consortium. COG-UK update on SARS-CoV-2 Spike mutations of special interest. 2020; Available from: https://www.cogconsortium.uk/wp-content/uploads/2020/12/Report-1_COG-UK_20-December-2020_SARS-CoV-2-Mutations_final_updated2.pdf.
Galvao, J., COVID-19: the deadly threat of misinformation. Lancet Infect Dis, 2020.
Browne, M., Epistemic divides and ontological confusions: The psychology of vaccine scepticism. Hum Vaccin Immunother, 2018. 14(10): p. 2540-2542.
World Health Organisation. Infodemic management. 2020; Available from: https://www.who.int/teams/risk-communication/infodemic-management.
Johns Hopkins University of Medicine Coronavirus Resource Center. COVID-19 Dashboard by the Center for Systems Science and Engineering (CSSE) at Johns Hopkins University (JHU) 2020; Available from: https://coronavirus.jhu.edu/map.html.
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